Legendary CARLOS SANTANA will begin a two-year run of unique performances - An Intimate Evening with Santana: Greatest Hits Live: Yesterday, Today & Tomorrow - in the specially re-configured House Of Blues at the Mandalay Bay Resort and Casino in Las Vegas beginning in May 2012.

Tickets go on sale Saturday, March 3 at 10 a.m. for a special series of shows by one of the greatest guitarists in rock history who will perform in an interactive intimate venue that will allow fans to rock with him throughout each evening.

“I am deeply honored that our new home in Las Vegas is The House of Blues at Mandalay Bay,” Carlos Santana said. “I have long admired their love of "the Blues" and that it is a world-class entertainment venue. We hope to honor and celebrate the diversity and brotherhood of world culture that the House of Blues promotes.

House of Blues Las Vegas at Mandalay Bay Resort and Casino has been uniquely reconfigured for the special Santana show. Fans within a few feet of Carlos can select from several intimate locations within the venue, from a limited number of exclusive VIP packages including meet and greets, limited edition photos, specialty dining/beverage packages and stage-side specialty dining.

The two-year residency kicks off on May 2 with a series of shows taking place throughout the months of May and June. The residency will then resume in September and play through 2013.

House of Blues Entertainment CEO Ron Bension said: “This will be a rare chance for music lovers to get this close to an amazing performer like Carlos Santana. Fans will be able to share a dance, a special moment, or sing out loud during this all night show.

For a list of confirmed dates, tickets, VIP packages or more info go to Santana.com.